Dyslipidaemia: Pathophysiology and types
Dyslipidaemia is a risk factor for premature cardiovascular disease. Cholesterol and triglycerides play an essential role in many biological functions and are transported around the body by lipoproteins. Measuring lipid and lipoprotein levels can help to assess cardiovascular risk and inform treatment.
Familial hypercholesterolaemia is the main cause of primary dyslipidaemia and early detection of both heterozygous and homozygous conditions is vital for preventing premature cardiovascular disease and death. Comorbidities, such as hypothyroidism and chronic kidney disease, can cause secondary dyslipidaemia, and poor diet and some medicines can also disrupt lipid levels.
Helen Williams is consultant pharmacist for cardiovascular disease, medicines management team, Southwark Clinical Commissioning Group.
Citation: Clinical Pharmacist DOI: 10.1211/CP.2013.11125079
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