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Diarrhoea vaccine in a patch

Travellers’ diarrhoea — often caused by enterotoxigenic Escherichia coli — could be prevented by pre-vaccination with a patch containing heat-labile toxins from E coli, a Lancet study suggests ().

Although the 170-patient study was not powered to test efficacy of this strategy, the researchers report that patients given the vaccine patch were less likely to have moderate-to-severe diarrhoea (P=0.0070) or severe diarrhoea (P=0.0332) than those given sham patches.

Citation: Electronicjuice URI: 10008226

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