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Nitazoxanide for rotavirus diarrhoea

A three-day course of nitazoxanide — a thiazolide anti-infective agent — reduces the duration of rotavirus diarrhoea in children, new data show (published online in , 13 June 2006).

Thirty-eight children aged five months to seven years (median age 11 months)admitted to hospital with rotavirus diarrhoea were randomised to receive eithernitazoxanide or placebo.

Median time to resolution of illness was 31 hours in the treatment group and75 hours in the control group (P=0.0137). No significant adverse events werereported.

Citation: Electronicjuice URI: 10022157

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