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If a patient wants to take a statin, and offering it is in line with national guidance, which one should be recommended?

By Chris Corfield

See also (first paper)  The effectiveness of statins for primary prevention in people without established cardiovascular disease

Chris Corfield is chief pharmacist at NHS Hammersmith and Fulham

email [email protected]



This paper, the second of two, aims to provide information to help pharmacists discuss economically important choices about which statin to use with prescribers. NICE guidelines recommend a specific first-choice statin and a dose for some indications, but not for others.


The paper highlights three relevant questions, suggests responses to them and suggests first- or second-line statin choices informed by those responses.


Included are Panels showing the cost of the various statins and the mean percentage reduction in LDL cholesterol achieved by simvastatin, atorvastatin and rosuvastatin.

The paper outlines three questions that are relevant to choices when greater LDL cholesterol reduction than is achievable with simvastatin 40mg daily is indicated, and provides suggested responses to those questions and a Table of suggested statin choices informed by those responses


Full text article (PDF 760K)

Citation: Electronicjuice URI: 11070338

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